PARS in Ophthalmology
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Ophthalmic imaging is critical for the study of eye disease and for vision health. Many eye diseases induce structural and functional changes in the retina, resulting in vision impairment and loss. New retinal imaging technologies are critical to understanding pathogenesis, and advancing early diagnosis. PARS retinal scanning provides both structural information on the vascular network, and functional information on retinal oxygen saturation and retinal metabolism.
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In Vivo Blood Oxygenation Saturation (mouse ear)
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PARS, Photon Absorption Remote Sensing is poised to revolutionize retinal imaging. PARS simultaneously captures both scattering and absorption contrasts without contact. By using dual excitation wavelengths that distinguish oxy- and deoxy-hemoglobin absorption, we capture hemoglobin distribution and oxygenation saturation to give unique structural and functional vascular images of the living tissue. We can measure blood flow rates using high frame video. We have shown this is feasible on phantoms and animal eyes, and are moving into imaging the human eye. To learn more about PARS Technology, visit our Technology page. |
Ophthalmology Clinical Advisory Board
Dr. Richard Weinstein, MD
Co-founder and Comprehensive Ophthalmologist at the Ocular Health Center in Kitchener-Waterloo, Canada Co-Founder of EyeStart Inc. |
Dr. Toby Chan, MD
Co- Division Head of Ophthalmology for St. Mary's General Hospital and Grand River Hospital in Kitchener Assistant Clinical Professor (adjunct) of Opthalmology at McMAster University. |
Dr. Jaspreet S. Rayat, MD
Assistant Clinical Professor (adjunct) of Ophthalmology at McMaster University, Department of Medicine Comprehensive Ophthalmologist and Cataract Surgeon. Co-Founder of EyeStart Inc. |
Related Publications
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2022 / 03 - Scientific Reports
In vivo functional and structural retina imaging using multiwavelength photoacoustic remote sensing microscopy. Zohreh Hosseinaee, Nicholas Pellegrino, Nima Abbasi, Tara Amiri, James A. Tummon Simmons, Paul Fieguth, Parsin Haji Reza Read / Download |
2021 / 06 - Scientific Reports
Functional and structural ophthalmic imaging using noncontact multimodal photoacoustic remote sensing microscopy and optical coherence tomography. Zohreh Hosseinaee, Nima Abbasi, Nicholas Pellegrino, Layla Khalili, Lyazzat Mukhangaliyeva, Parsin Haji Reza Read / Download |
2020 / 11 - Optics Letters
Label-free, non-contact, in vivo ophthalmic imaging using photoacoustic remote sensing microscopy. Zohreh Hosseinaee, Layla Khalili, James A. Tummon Simmons, Kevan Bell, Parsin Haji Reza Read / Download |