Our Technology
MLI™ (Multi-Laser Imaging) is a Transformative Imaging Device
for Life Science Research, Digital Pathology, Fresh Tissue Diagnostics and Eye Imaging
for Life Science Research, Digital Pathology, Fresh Tissue Diagnostics and Eye Imaging
MLI is the most advanced optical absorption imaging device to date. It captures optical absorption from radiative contrast (e.g., autofluorescence),
non-radiative relaxation (e.g., temperature, pressure) and scattering channels (indirect optical absorption measurement) simultaneously without contact with the tissue.
MLI is built on the research and development of PARS (photon absorption remote sensing), a proprietary technology independently invented and owned by illumiSonics Inc.
non-radiative relaxation (e.g., temperature, pressure) and scattering channels (indirect optical absorption measurement) simultaneously without contact with the tissue.
MLI is built on the research and development of PARS (photon absorption remote sensing), a proprietary technology independently invented and owned by illumiSonics Inc.
HOW MLI WORKS
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A picosecond scale pulsed excitation laser is focused into biological tissues to generate radiative (i.e., optical emissions), non-radiative (i.e., heat and pressure), and scattering effects in the sample.
Absorbed photons are captured and converted into different forms of emission from the sample (non-radiative and radiative), while scattered photons continue moving through and interacting with other portions of the sample. |
Non-radiative effects are recorded using a secondary confocal detection beam, enabling the detection of temperature and pressure changes as close to the source as possible. These changes are registered as modulations in backscattering intensity, which are then directly correlated to the local non-radiative absorption contrast.
The unperturbed backscatter (pre-excitation event) simultaneously captures the optical scattering contrast. |
All captured contrasts can then be combined or visualized separately.
