MLI® of Endometriosis

Unenhanced MLI® of an unstained pelvic biopsy specimen readily identifies areas of endometriosis. 

Both the unenhanced MLI® and H&E-stained photomicrograph demonstrates histologic features consistent with endometriosis in a endoscopic biopsy of pelvic tissue.  The section shows ectopic endometrial-type glands with a rim of endometrial stroma embedded in a background of dense fibroconnective tissue. The glands are irregular and elongated, lined by columnar epithelial cells with basally oriented nuclei, resembling endometrial glands.  

Surrounding the glands is endometrial-type stroma composed of small, uniform spindle cells, which supports the diagnosis of endometriosis when present together with glandular elements. The adjacent tissue demonstrates fibrosis. 

Image Credit: illumiSonics Inc.